Below some books I found interesting to read and used to make this site.
Holger Gohlke (Editor)
Wiley; june 2012, 359 pages; E-book and hardcover
Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a comparison of key experimental methods (calorimetry, surface plasmon resonance, NMR) used in generating interaction data. The second half of the book is devoted to insilico methods of modeling and predicting molecular recognition and binding, ranging from first principles-based to approximate ones. Here, as elsewhere in the book, emphasis is placed on novel approaches and recent improvements to established methods. The final part looks at unresolved challenges, and the strategies to address them. With the content relevant for all drug classes and therapeutic fields, this is an inspiring and often-consulted guide to the complexity of protein-ligand interaction modeling and analysis for both novices and experts.
|Real-Time Analysis of Biomolecular interactions - Applications of Biacore
Nagata, K. & Handa, H.
Springer-Verlag 2000, 256 p., hardcover
General introduction to surface plasmon resonance and the Biacore system and some basics of the experimental procedure. Greater part consist of the applications with SPR and Biacore. Applications are explaned by real experiments and data analysis and contain a reference list.
|Immobilized Biomolecules in Analysis - A Practical Approach
Cass, T. & Ligles, F.S.
Oxford University Press 1998, 216 p., paperback
This book describes in detail key methods for immobilization of biomolecules and cells on a variety of surfaces with different geometries and chemistries so that they retain their function. Also included are the analytical techniques needed to measure the functionality of immobilized biomolecules.
|Surface Plasmon Resonance Based Sensors
Series: Springer Series on Chemical Sensors and Biosensors, Vol. 4
Homola, Jirí (Ed.)
Springer 2006, XII, 251 p., hardcover
Also available online
The book is divided into three parts. Part I introduces readers to the fundamental principles of surface plasmon resonance (bio)sensors and covers the electromagnetic theory of surface plasmons, the theory of SPR sensors and molecular interactions at sensor surfaces. Part II presents a review of the state of the art in the development of SPR sensor instrumentation and functionalization methods. Part III discusses applications of SPR biosensors for study of molecules and their interactions and detection of chemical and biological analytes related to environmental monitoring, food safety and security and medical diagnostics.
|Binding and Kinetics for Molecular Biologists
J.A. Goodrich, J.F. Kugel
Cold Spring Harbor Laboratory Press 2007, 177 p., hardcover spiral
This book offers a pratical guide to the principles of quatitative analysis in biological experiments. Topics covered range from the basics, such as measuring the concentrations of macromolecules, through considerations of binding constants and the kinetics of molecular interactions.
Complimenting the material presented in the book is a collection of Web-based simulations, available at the CFH site, that can be manipulated to visualize important concepts presented in the chapters. They afford a better understanding of binding and rate curves and fitting data.
|Enzyme structure and mechanisms
Alan Fersht, W.H. Freeman and company New York 1985
|Protein-Protein Interactions, A Molecular Cloning Manual, 2nd edition;
Editors, Erica Golemis and Peter Adams, Cold Spring Harbor Laboratory Press.
|Bioconjugate Techniques (2nd edition, 2008) is a book that is widely recognized as the best single source of information about the chemistry and research methods of biomolecular crosslinking, surface attachment and labeling. Goto reference|