Forum :: Shear stress during SPR


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This forum is intended for questions about kinetics, Surface Plasmon Resonance and the instruments related to these techniques.

TOPIC: Shear stress during SPR

Shear stress during SPR 01 Apr 2014 19:18 #1

I was wondering whether there is some information about the possible effect that shear stress forces in the microfluidic cell during SPR analysis might have on the conformation of the injected protein....
All the best,
Vincenzo De Filippis

Dept. Pharma Sciences,
Prof. of Biochemistry
University of Padua, Italy

Shear stress during SPR 02 Apr 2014 20:58 #2

The only molecule I know that changes under shear stress is von Willebrand Factor (vWF).
You can search PubMed under 'shear stress vwf'.

regards
Arnoud
Moderators: Arnoud