Sensor chip SA


The SA sensor chips make use of the strong binding between biotin and (strep)avidin.

Nilsson, P. et al. Real-time monitoring of DNA manipulations using biosensor technology. Analytical Biochemistry 224: 400-408; (1995).

Real time monitoring of DNA manipulations. Using sensor chip SA with streptavidin bound to the surface it is possible to immobilize 5' biotinylated oligonuleotides. With this as a basis, DNA manipulations such as oligo annealing, oligo hybridization, DNA ligation, DNA synthesis and cleavage with endonucleases can be investigated.


Charvolin, D. et al. The use of amphipols as universal molecular adapters to immobilize membrane proteins onto solid supports . Proc.Natl.Acad.Sci.U.S.A 106: 405-410; (2009).

The use of amphipols as universal molecular adapters to immobilize membrane proteins onto solid supports