XanTec 3D surface


XanTec 3D hydrogel sensor chips

In the table below the 3D hydrogel sensor chips available at XanTec (1) are shown. Several surface thicknesses are offered and in addition three surface densities are available: Low, Medium and Dense. 3 D immobilization matrices allow multilayer ligand immobilization which leads to significant signal amplification. They are employed for qualitative screening, concentration determinations and detection and kinetic analysis of low molecular weight compounds. As a rule of thumb, the smaller the analyte is, the thicker and denser the hydrogel structure should be.

XanTec flat
XanTec flat surface
Table: 3D hydrogel surfaces
Name Surface coating Functionalities Thickness (nm) Densities*
AHC Polycarboxylate partially amino modified 30, 200, 1000       M
AD CM dextran partially amino modified 50, 200, 500   L, M, D
AG Agarose hydrogel hydroxy approx. 200   -
AL Alginate hydrogel carboxyl approx. 100   -
BHC Polycarboxylate biotin 30, 200, 1000       M
C Polycarboxylate, high charge density carboxyl 30, 80, 200       M, D
CMC Cellulose carboxymethyl approx. 200   -
CMD CM dextran carboxymethyl 50, 200, 500   L, M, D
CMPEG Polyethyleneglycol, 6kDa carboxymethyl approx. 100   -
CS Polycarboxylate, partially sulfonated carboxyl 30, 80, 150       M, D
D Dextran hydroxyl 50, 200, 500   L, M, D
GEL Gelatine - approx 200.   -
HC Polycarboxylate, medium charge density carboxyl 30, 200, 1000, 1500       M
HLC Polycarboxylate, low charge density carboxyl 30, 200, 1000       M
HZHC Polycarboxylate hydrazide modified 30, 200, 1000       M
HEP Heparinl carboxyl approx. 50   -
NIHC Polycarboxylate NTA polyvalent 30, 200, 1000       M
NID CM dextran NTA 50, 200, 500   L, M, D
PAHC Polycarboxylate proteine A 30, 200,1000       M
PAD CM dextran brush conformation proteine A 50, 200, 500   L, M
PC Pectin hydrogel carboxyl approx 200   -
PEG Polyethyleneglycol, 6 kDa hydroxyl approx 100   -
PLY Poly-L-lysine primary amine approx. 300   -
SAHC Polycarboxylate streptavidn 30, 200, 1000       M
SAD CM dextran streptavidin 50, 200, 500   L, M, D
THC Polycarboxylate disulfide modified 30, 200, 1000       M
TD CM dextran disulfide modified 50, 200, 500   L, M, D

*Densities L: low; M: medium; D: dense / Not all combinations are available.

References

(1)  XanTec - XanTec website. (2012). Goto reference