Biacore sensor chips
In the Biacore SPR instruments a wide range of sensor surfaces can be used. The actual sensor surface is shielded within a protective sheet. The surfaces range from plain gold to several types of carboxylated dextran matrices and specialized surfaces such as protein G, NTA or streptavidin. In addition, lipophilic surface are also available.
| Chip name | Dextran | Modification | Application |
|---|---|---|---|
| CM7 | 100 nm | 100% carboxylation | high density CM-dextran - high capacity |
| CM5 | 100 nm | 100% carboxylation | general |
| CM4 | 100 nm | 30% carboxylation | cell extracts / serum and membranes |
| CM3 | 30 nm | 100% carboxylation | cell extracts / serum and membranes |
| C1 | none | 100% carboxylation | phage binding |
| NTA | 100 nm | NTA | capturing poly HIS-groups |
| HPA | none | hydrophobic | lipid capturing |
| L1 | 100 nm | lipophilic substances | bilayers to mimic membranes |
| SA | 100 nm | streptavidin | capturing of biotin |
| CAP | 100 nM | oligopeptide | oligopeptide mediated capture of biotin |
| AU | none | none | user defined surface chemistry |
| SIA | none | none | surface interaction analysis in material science |