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The combination of BIA and MS can be a powerful tool to identify molecular interaction partners.

Nedelkov, D. and Nelson, R. W.. Analysis of native proteins from biological fluids by biomolecular interaction analysis mass spectrometry (BIA/MS): exploring the limit of detection, identification of non-specific binding and detection of multi-protein complexes. Biosens.Bioelectron. 16: 1071-1078; (2001).


Tudos, A. J. et al. Rapid surface plasmon resonance-based inhibition assay of deoxynivalenol. J.Agric.Food Chem. 51: 5843-5848; (2003).